T-Cell Recognition of Human Melanoma Antigens
نویسندگان
چکیده
منابع مشابه
Dual recognition of a human cytotoxic T-cell clone for melanoma antigens.
It is well known that tumor-specific CTLs have a crucial role in the elimination of tumors and that different CTL populations recognize tumor antigens in MHC-restricted and MHC-unrestricted manners. We have established two alpha beta CTL clones that recognize melanoma antigens in both human lymphocyte antigen (HLA)-A2-restricted and HLA-unrestricted manners. Flow cytometry analysis showed that ...
متن کاملMelanoma Antigens Dual Recognition of a Human Cytotoxic T-Cell Clone for Updated Version
It is well known that tumor-specific CTLs have a crucial role in the elimination of tumors and that different CTL populations recognize tu mor antigens in MHC-restricted and MHC-unrestricted manners. We have established two aßCTL clones that recognize melanoma antigens in both human lymphocyte antigen (HLA)-A2-restricted and HLA-unrestricted manners. Flow cytometry analysis showed that these C...
متن کاملRecognition of Histoplasma capsulatum yeast-cell antigens by human lymphocytes and human T-cell clones.
We have prepared a detergent extract from the cell wall and cell membrane of Histoplasma capsulatum yeast cells that is recognized by T cells from mice immunized with viable organisms or with the extract. A 62-kd antigen from this extract has been isolated and has been shown to be antigenic and to confer protective immunity in mice. In this study, we examined the in vitro proliferative response...
متن کاملCell surface antigens of human malignant melanoma. III. Recognition of autoantibodies with unusual characteristics
The sera of three patients with malignant melanoma showing reactivity with surface antigens of cultured autologous melanoma cells were analyzed by mixed hemadsorption and immune adherence assays in conjunction with absorption tests. In contrast to the melanoma-specific antigens demonstrated previously, the surface antigens detected by these sera occurred on a broad range of nucleated cells, bot...
متن کاملHomologous Mouse and Human T Cell Antigens
The mouse Lyt-1, Lyt-2, and Lyt-3 lymphocyte surface antigens have been used for some years now as immunogenet ic markers whose selective expression distinguishes maturat ional and functional T cell subpopulations (1, 2). Lyt-2 and Lyt-3, for example, are selectively expressed on cytotoxic and suppressor T cells but are not found on helper T cells (3, 4). Similarly, cytotoxic depletion studies ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Immunotherapy
سال: 1993
ISSN: 1524-9557
DOI: 10.1097/00002371-199308000-00002